The Role of Biochemical Parameters, Body Fat, and Comorbidities in Health-Related Quality of Life among Haemodialysis Patients.
DOI:
https://doi.org/10.70672/dn0maa30Keywords:
Biochemical parameters, body fat, haemodialysis, HRQOLAbstract
Introduction: Health-related quality of life (HRQOL) is often compromised in patients with end-stage renal disease (ESRD), despite the life-saving benefits of haemodialysis (HD). Although poor nutritional status is prevalent among HD patients, the association between HRQOL and specific factors, such as biochemical parameters, body fat, and comorbidities, remains insufficiently explored. This study aimed to examine the correlations between these factors and HRQOL in HD patients. Methods: A cross-sectional study involving 97 ESRD patients from two HD centres in an urban area of Selangor was conducted to ascertain the correlation between HRQOL and nutritional status. Data on socio-demographic characteristics, anthropometric measurements, biochemical parameters, and medical history were collected. HRQOL was evaluated using the Kidney Disease Quality of Life Short Form (KDQOL-SFTM version 1.3). Results: The mean KDQOL-SF™ scores ranged from 30.41 ± 29.37 to 85.91 ± 16.38. The mean scores for physical composite summary (PCS) and mental composite summary (MCS) were 40.89 ± 9.77 and 47.17 ± 9.84, respectively. Significant differences in HRQOL were observed across socio-demographic characteristics with the exception of gender and money allowance. Positive correlations with HRQOL were found for serum phosphorus, sodium, creatinine, albumin, HDL-cholesterol, and duration of ESRD diagnosis. Meanwhile, serum chloride, total iron-binding capacity (TIBC), transferrin, body fat, and the number of comorbidities were inversely correlated with HRQOL. Conclusion: This study highlights the role of biochemical parameters, body fat, and comorbidities on HRQOL in haemodialysis patients, emphasizing the need for regular monitoring and targeted interventions to enhance HRQOL and overall patient outcomes.
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