Remitting Seronegative Symmetrical Synovitis with Pitting Oedema (RS3PE) in a Young Patient Mimicking Syphilitic Arthritis: A Case Report.

Authors

  • Wahinuddin Sulaiman Faculty of Medicine, Universiti Kuala Lumpur Royal College of Medicine Perak, Malaysia.
  • Ding Chek Lang Department of Medicine, KPJ Ipoh Specialist Hospital, Ipoh, Perak, Malaysia.

DOI:

https://doi.org/10.70672/tdqnhy18

Keywords:

Corticosteroid, Reactive arthritis, RS3PE, Sexual transmitted disease, Syphilis, Young.

Abstract

Remitting seronegative symmetrical synovitis with pitting oedema (RS3PE) is a rare disorder characterized by acute symmetrical synovitis involving both hands and feet, accompanied by pitting oedema. The aetiopathogenesis of RS3PE is still obscured. It commonly occurs in individuals over 50 years of age and has a good prognosis. RS3PE responds well to corticosteroid. We report a case of a young male being treated for sexually transmitted disease (STD) who presented with recurrent episodes of bilateral leg oedema and symmetrical joint pain involving the ankles and hands. He was successfully treated with corticosteroid. Reactive arthritis was excluded in view of the recurrent episodes with no evidence of all phases of syphilis, especially tertiary syphilis.

References

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Published

28-05-2025

Issue

Section

Case Report

How to Cite

Wahinuddin Sulaiman, & Ding Chek Lang. (2025). Remitting Seronegative Symmetrical Synovitis with Pitting Oedema (RS3PE) in a Young Patient Mimicking Syphilitic Arthritis: A Case Report. Asian Journal of Medicine & Health Sciences, 8(1). https://doi.org/10.70672/tdqnhy18