Granulomatous with Polyangiitis (GPA) Presenting with Mononeuritis Multiplex: A Case-based Review.
DOI:
https://doi.org/10.70672/y248kp85Keywords:
c-ANCA, Granulomatosis with polyangiitis, Mononeuritis multiplex.Abstract
Granulomatosis with polyangiitis (GPA), formerly known as Wegener's granulomatosis (WG), is a rare rheumatological disease that can affect individuals of any age. ANCA associated vasculitis (AAV) with granulomatous with polyangiitis proteinase 3 (GPA-PR3) is present in approximately 85-90% of cases. We report a 52-year-old Indian female with positive cytoplasmic-antineutrophil cytoplasmic antibody (c-ANCA) presented with chronic sinusitis, orbital cellulitis, and mononeuritis multiplex of the right foot and possible sensorineural defect hearing impairment.
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