Portal Vein Thrombosis in Pregnancy with Protein S Deficiency: a Case Report with Literature Review

Abstract

Portal vein thrombosis is uncommon in general population and rare in pregnancy. Inherited thrombophilia is a genetic condition that increase the risk of thromboembolic disease especially during pregnancy. The usage of hormone therapy in a thrombophilic patient in pregnancy may further potentiate the occurrence of thromboembolism. We report a case of a pregnant woman who developed an acute portal vein thrombosis due to protein S deficiency and aggravated by the usage hormone therapy during pregnancy. The patient was successfully treated with low molecular weight heparin therapy.