NOVEL MURINE PARAMYXOVIRUSES

Abstract

Many paramyxovirus pathogens jump species, causing resurging or re-emerging diseases in spillover hosts including humans. Novel murine J virus and Mojiang paramyxovirus can infect humans causing subclinical and fatal diseases, respectively. This review focuses on seven novel murine paramyxoviruses: J virus, Mojiang paramyxovirus, Nariva virus, Mossman virus, Rodent Paramyxovirus of Zambia, Beilong virus, and Tailam virus, that had been isolated since 1960s. The methods for data mining using ProQuest, PubMed, Clinical key and other searches revealed the history of the first isolations, host species, propagation systems and genetics of the novel murine viruses. Further studies will give better understanding on the geographical distributions, evolution and biology of the paramyxoviruses which can be a potentially useful biological resource for disease research, like their well-characterized relative, the murine Sendai virus.